Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
PPM1B
Protein phosphatase, Mg2+/Mn2+ dependent 1BPP2CB, PP2CBETA, PPC2BETAX
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Novus Biologicals |  H00005495-M01 |
1 references | Monoclonal |
WB
EL
ICC
IP
BN
PLA
|
|
| Abnova Corporation | H00005495-M01 |
Monoclonal |
WB
EL
ICC
IP
PLA
|
||
| antibodies-online | ABIN393440 |
Monoclonal |
WB
EL
ICC
IP
IHC
|
||
| Proteintech Group | 13193-1-AP |
2 references | Polyclonal |
WB
EL
ICC
IHC
|
|
| Invitrogen Antibodies | PA5-29263 |
Polyclonal |
WB
ICC
IHC
ChIP
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider