327902

antibody from BioLegend

Targeting: ITGAV CD51, MSK8, VNRA, VTNR

ELISA

Immunoprecipitation

Antibody data

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Validation data

Product number: 327902 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#327902, RRID:AB_2129615
Product name: Purified anti-human CD51
Antibody type: Monoclonal
Antigen: Melonama cells
Description: CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor α chain, or integrin αV. It forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its β chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling, mediates bone absorption and angiogenesis.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C.

ITGAV protein structure - 327902 shown in red.