Tissue expression
Cell line expression
Protein structure
SHMT2
Serine hydroxymethyltransferase 2SHMT
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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Atlas Antibodies | HPA020543 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Proteintech Group | 11099-1-AP | 13 references | Polyclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | PA5-32228 | 2 references | Polyclonal |
WB
ICC
IHC
OA |
|
GeneTex | GTX125939 | 2 references | Polyclonal |
WB
ICC
IHC
|
|
Novus Biologicals | NBP1-80754 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider