Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3LH3
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Proteintech Group |  11027-1-AP |
29 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
| Invitrogen Antibodies | 11027-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
|
||
| NovoPro Bioscience Inc. | 107477 |
Monoclonal |
WB
EL
ICC
IP
IHC
|
||
| Wuhan Fine Biotech Co., Ltd. | FNab06553 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
||
| Novus Biologicals | H00008985-B01P |
2 references | Polyclonal |
WB
ICC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider