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ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunitEM9, MAG, MGC102762, MGC126218, MGC126219, XPD
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Top validated antibodies |
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| Proteintech Group |  10818-1-AP |
9 references | Polyclonal |
WB
EL
IP
IHC
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| LSBio | LS-C375659 |
Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | 10818-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Novus Biologicals | 25850002 |
2 references | Polyclonal |
WB
EL
IHC
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| NovoPro Bioscience Inc. | 110408 |
Polyclonal |
WB
EL
IP
IHC
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