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XRCC4
X-ray repair cross complementing 4The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. [provided by RefSeq, Oct 2019]
Top validated antibodies |
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| Atlas Antibodies |  HPA006801 |
2 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-27104 |
1 references | Polyclonal |
WB
ICC
IP
IHC
OA
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| Proteintech Group | 15817-1-AP |
8 references | Polyclonal |
WB
EL
IP
IHC
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| NSJ Bioreagents | RQ7416 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX109632 |
4 references | Polyclonal |
WB
ICC
IHC
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