Tissue expression
Cell line expression
Protein structure

OAZ1

Ornithine decarboxylase antizyme 1
AZ1, AZI, MGC138338, OAZ 
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene. [provided by RefSeq, Dec 2014]
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147 antibodies from 26 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Biorbyt
38 antibodies
antibodies-online
49 antibodies
Atlas Antibodies
1 antibody
Novus Biologicals
2 antibodies
Aviva Systems Biology
2 antibodies
Invitrogen Antibodies
4 antibodies
GeneTex
2 antibodies
St John's Laboratory
4 antibodies
Cusabio Biotech Co., Ltd
3 antibodies
Enzo Life Sciences
2 antibodies
Bioworld Technology, Inc
2 antibodies
Everest Biotech
2 antibodies
Antibodies.com
1 antibody
RabMAbs
1 antibody
Creative Biolabs
2 antibodies
Abnova Corporation
1 antibody
OriGene
1 antibody
Boster Biological Technology
2 antibodies
MyBioSource
2 antibodies
Abbexa
5 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Creative Diagnostics
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
United States Biological
1 antibody
Acris Antibodies GmbH
2 antibodies