BS8904

antibody from Bioworld Technology, Inc

Targeting: OAZ1 AZ1, AZI, MGC138338, OAZ

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8904

Provider

Bioworld Technology, Inc

Product name

OAZ1 polyclonal antibody

Antibody type

Polyclonal

Antigen

Ornithine decarboxylase antizyme 1; ODC-Az; OAZ1; OAZ

Description

Antizyme 1 (AZ1) negatively regulates polyamine synthesis by enhancing the negative feedback loop controlling ornithine decarboxylase (ODC) activity. Polyamines are involved in cell cycle and cell growth, and thus the interaction between AZ1 and ODC functions in this process as well, in a regulatory manner. Furthermore, treatment of cells with leptomycin B, an inhibitor of chromosomal maintenance proteins, causes the relocation of AZ1 to the nucleus, suggesting a novel function of AZ1 not associated with the proteasome.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.