S100A11

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008]

Description

S100 calcium binding protein A11

Tissue specificity

Tissue enhanced (esophagus)

Subcell location

Nucleoplasm, Nuclear speckles, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (152032506 - 152047907)

Ensembl ID

ENSG00000163191  (ver. 103.38)

Orthologs

Mouse S100a11: ENSMUSG00000027907

UniProt

P31949

neXtProt

NX_P31949

Human splice variants
Mouse splice variants

Protein structure