Ab175651

antibody from Aladdin Scientific Corporation

Targeting: IL6R CD126

No application information provided.

Antibody Data

Product number

Ab175651

Provider

Aladdin Scientific Corporation

Product name

Satralizumab (anti-IL-6Ra)

Antibody type

Recombinant

Description

Satralizumab (anti-IL-6RA), a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab (anti-IL-6RA) prevents dTAA formation and progression in rattus norvegicus. Satralizumab (anti-IL-6RA) can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research.Purity³95% (SDS-PAGE&SEC)Endotoxin Level²1.0EU/mgProtein FunctionPart of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.

Reactivity

Human

Conjugate

Unconjugated

Vial size

100_g,10mg,1mg,5mg

Concentration

Lot by Lot

Storage

Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.