Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- ELISA [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- H00197259-M02 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00197259-M02, RRID:AB_2145456
- Product name
- Mouse Monoclonal MLKL Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. MLKL - mixed lineage kinase domain-like (3B2)
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Antitumor activity of HPA3P through RIPK3-dependent regulated necrotic cell death in colon cancer.
ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis.
Cho E, Lee JK, Park E, Seo CH, Luchian T, Park Y
Oncotarget 2018 Jan 30;9(8):7902-7917
Oncotarget 2018 Jan 30;9(8):7902-7917
ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis.
Ma B, Marcotte D, Paramasivam M, Michelsen K, Wang T, Bertolotti-Ciarlet A, Jones JH, Moree B, Butko M, Salafsky J, Sun X, McKee T, Silvian LF
PloS one 2016;11(11):e0165983
PloS one 2016;11(11):e0165983
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: MLKL Antibody (3B2) [H00197259-M02] - Detection limit for recombinant GST tagged MLKL is 0.3 ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MLKL Antibody (3B2) [H00197259-M02] - Analysis of monoclonal antibody to MLKL on formalin-fixed paraffin-embedded human colon. Antibody concentration 3 ug/ml.