Tissue expression
Cell line expression
Protein structure
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2D15F37S1, jdf2, p528
This gene belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16. [provided by RefSeq, Mar 2012]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
2 references | Monoclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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Bethyl Laboratories | ![]() |
Polyclonal |
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