abx004253

antibody from Abbexa
Targeting: PSMF1 PI31
Provider product page for abx004253
Western blot
Immunohistochemistry

Antibody data

Product number
abx004253 - Provider product page
Provider
Abbexa
Product name
Proteasome Inhibitor Subunit 1 (PSMF1) Antibody
Antibody type
Polyclonal
Description
PSMF1 Antibody is a Rabbit Polyclonal antibody against PSMF1. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µl
Concentration
> 1 mg/ml
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
PSMF1 protein structure - abx004253 shown in red.