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Protein structure
KLRC3
Killer cell lectin like receptor C3NKG2-E
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  H00003823-M01 |
2 references | Monoclonal |
WB
EL
FC
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| antibodies-online | ABIN395957 |
5 references | Monoclonal |
WB
EL
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| Cusabio Biotech Co., Ltd | CSB-PA23099A0Rb |
Polyclonal |
EL
ICC
IHC
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| Abnova Corporation | H00003823-M01 |
1 references | Monoclonal |
EL
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| LSBio | LS-C680740 |
Polyclonal |
EL
ICC
IHC
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