AMM03724G

antibody from Leading Biology

Targeting: KLRC3 NKG2-E

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03724G

Provider

Leading Biology

Product name

KLRC3 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3D5

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.