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Protein structure
UBR1
Ubiquitin protein ligase E3 component n-recognin 1The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  H00197131-M01 |
2 references | Monoclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN566929 |
1 references | Monoclonal |
WB
EL
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| Abnova Corporation | H00197131-M01 |
1 references | Monoclonal |
WB
EL
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| Invitrogen Antibodies | 26069-1-AP |
Polyclonal |
IP
IHC
OA
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| Proteintech Group | 26069-1-AP |
Polyclonal |
EL
IP
IHC
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