CABT-B11654

antibody from Creative Diagnostics

Targeting: TPP1 CLN2, LPIC, SCAR7, TPP-1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B11654

Provider

Creative Diagnostics

Product name

Mouse anti-Human TPP1 monoclonal antibody, clone 4C2

Antibody type

Monoclonal

Description

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4C2

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.