Tissue expression
Cell line expression
Protein structure
NTAN1
N-terminal asparagine amidaseThe protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Top validated antibodies |
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Novus Biologicals | NB100-77673 | 19 references | Monoclonal |
WB
IP
IHC
|
|
antibodies-online | ABIN2660531 | Monoclonal |
WB
ICC
IHC
FC |
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Cusabio Biotech Co., Ltd | CSB-PA822176LA01HU | Polyclonal |
EL
ICC
IHC
|
||
Biorbyt | orb423107 | Polyclonal |
EL
ICC
IHC
|
||
GeneTex | GTX119378 | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider