BS8169

antibody from Bioworld Technology, Inc

Targeting: GP2 ZAP75

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8169

Provider

Bioworld Technology, Inc

Product name

GP2 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human GP2.

Description

GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein that is expressed in pancreatic secretory (zymogen) granules, and is cleaved then released into the pancreatic duct along with exocrine secretions. GP2 interacts with syncollin and to type 1 fimbria of bacteria, a bacterial adhesin that is commonly expressed by members of the Enterobacteriacae family. Containing an EGF-like domain and a ZP domain, GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases, and the GP2-dependent transcytotic pathway may provide a new target for the development of M-cell-targeted mucosal vaccines. GP2 exists as four alternatively spliced isoforms that are desginated isoform 1, isoform beta, isoform alpha and isoform 2.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.