TAC1

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Description

Tachykinin precursor 1

Tissue specificity

Group enriched (brain, lymphoid tissue)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

7 (97732084 - 97740472)

Ensembl ID

ENSG00000006128  (ver. 103.38)

Orthologs

Mouse Tac1: ENSMUSG00000061762

UniProt

P20366

neXtProt

NX_P20366

Human splice variants
Mouse splice variants

Protein structure