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Learn11462-1-AP
antibody from Proteintech Group
Targeting: SKIV2L
170A, DDX13, HLP, SKI2W, SKIV2, SKIV2L1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 11462-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11462-1-AP, RRID:AB_2187472
- Product name
- SKIV2L antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SKIV2L antibody (Cat. #11462-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses.
Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway.
IL-1β/ATF3-mediated induction of Ski2 expression enhances hepatitis B virus x mRNA degradation.
RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism.
The SKIV2L RNA exosome limits activation of the RIG-I-like receptors.
The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells.
A genetic variant in the SKIV2L gene is significantly associated with age-related macular degeneration in a Han Chinese population.
Weston S, Baracco L, Keller C, Matthews K, McGrath ME, Logue J, Liang J, Dyall J, Holbrook MR, Hensley LE, Jahrling PB, Yu W, MacKerell AD Jr, Frieman MB
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 1;117(48):30687-30698
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 1;117(48):30687-30698
Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway.
Nogimori T, Nishiura K, Kawashima S, Nagai T, Oishi Y, Hosoda N, Imataka H, Kitamura Y, Kitade Y, Hoshino SI
Nucleic acids research 2019 Jan 10;47(1):432-449
Nucleic acids research 2019 Jan 10;47(1):432-449
IL-1β/ATF3-mediated induction of Ski2 expression enhances hepatitis B virus x mRNA degradation.
Shiromoto F, Aly HH, Kudo H, Watashi K, Murayama A, Watanabe N, Zheng X, Kato T, Chayama K, Muramatsu M, Wakita T
Biochemical and biophysical research communications 2018 Sep 10;503(3):1854-1860
Biochemical and biophysical research communications 2018 Sep 10;503(3):1854-1860
RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism.
Aly HH, Suzuki J, Watashi K, Chayama K, Hoshino S, Hijikata M, Kato T, Wakita T
The Journal of biological chemistry 2016 Jul 29;291(31):15958-74
The Journal of biological chemistry 2016 Jul 29;291(31):15958-74
The SKIV2L RNA exosome limits activation of the RIG-I-like receptors.
Eckard SC, Rice GI, Fabre A, Badens C, Gray EE, Hartley JL, Crow YJ, Stetson DB
Nature immunology 2014 Sep;15(9):839-45
Nature immunology 2014 Sep;15(9):839-45
The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells.
Saito S, Hosoda N, Hoshino S
The Journal of biological chemistry 2013 Jun 14;288(24):17832-43
The Journal of biological chemistry 2013 Jun 14;288(24):17832-43
A genetic variant in the SKIV2L gene is significantly associated with age-related macular degeneration in a Han Chinese population.
Lu F, Shi Y, Qu C, Zhao P, Liu X, Gong B, Ma S, Zhou Y, Zhang Q, Fei P, Xu Y, Hu J, Fan Y, Lin Y, Zhu X, Yang Z
Investigative ophthalmology & visual science 2013 Apr 26;54(4):2911-7
Investigative ophthalmology & visual science 2013 Apr 26;54(4):2911-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SKIV2L antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SKIV2L. This antibody recognizes human,mouse,rat antigen. The SKIV2L antibody has been validated for the following applications: ELISA, WB analysis.
