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PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1LH1, LLH, PLOD
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Top validated antibodies |
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| antibodies-online |  ABIN2845847 |
1 references | Polyclonal |
WB
IHC
FC
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| Proteintech Group | 12475-1-AP |
5 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NBP2-38770 |
2 references | Polyclonal |
WB
IHC
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| NovoPro Bioscience Inc. | 123554 |
Polyclonal |
WB
EL
IHC
FC
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| Invitrogen Antibodies | 29480-1-AP150UL |
Polyclonal |
WB
ICC
IHC
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