Tissue expression
Cell line expression
Protein structure
FBN1
Fibrillin 1FBN, MASS, MFS1, OCTD, SGS, WMS
This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016]
Top validated antibodies |
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Invitrogen Antibodies | MA5-12770 | 24 references | Monoclonal |
WB
ICC
IHC
IEM
OA
|
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GeneTex | GTX23090 | 2 references | Monoclonal |
WB
ICC
IHC
IEM |
|
Atlas Antibodies | HPA021057 | 3 references | Polyclonal |
ICC
IHC |
|
NovoPro Bioscience Inc. | 140401 | Monoclonal |
WB
EL
ICC
IP
IHC
|
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Novus Biologicals | NB110-8146 | 3 references | Monoclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider