DMAB8368

antibody from Creative Diagnostics

Targeting: FBN1 FBN, MASS, MFS1, OCTD, SGS, WMS

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DMAB8368

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DMAB8368, RRID:AB_2392147

Product name

Anti-Fibrillin monoclonal antibody, clone 12D2.4

Antibody type

Monoclonal

Description

The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.1 In immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 12D2.4 labels the elastic framework and more specifically the oxytalantic network close to the epidermis.

Reactivity

Bovine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

12D2.4

Vial size

200 _g

Storage

The purified (UNLB) antibody is supplied as 0.2 mg of purified immunoglobulin in 1.0 mL of 100 Mm borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8°C.