Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
HCST
Hematopoietic cell signal transducerDAP10, DKFZP586C1522, KAP10, PIK3AP
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Biorbyt |  orb449356 |
Polyclonal |
WB
EL
ICC
IHC
|
||
| Novus Biologicals | NB100-55403 |
1 references | Polyclonal |
WB
EL
|
|
| Invitrogen Antibodies | BS-15430R |
Polyclonal |
WB
EL
IHC
FC
|
||
| antibodies-online | ABIN188679 |
1 references | Polyclonal |
WB
EL
|
|
| Abnova Corporation | PAB7141 |
1 references | Polyclonal |
WB
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider