MAGEA6

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Description

MAGE family member A6

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular

Protein family

Cancer-related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X (152766136 - 152769747)

Ensembl ID

ENSG00000197172  (ver. 103.38)

Orthologs

-

UniProt

P43360

neXtProt

NX_P43360

Human splice variants

Protein structure