DHX37

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. [provided by RefSeq, Jul 2008]

Description

DEAH-box helicase 37

Tissue specificity

Low tissue specificity

Subcell location

Nuclear membrane

Predicted location

Intracellular

Protein family

Disease related genes
Enzymes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Potential drug targets
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

12 (124946825 - 124989131)

Ensembl ID

ENSG00000150990  (ver. 103.38)

Orthologs

Mouse Dhx37: ENSMUSG00000029480

UniProt

Q8IY37

neXtProt

NX_Q8IY37

Human splice variants
Mouse splice variants

Protein structure