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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Immunocytochemistry [1]
- Immunohistochemistry [8]
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- Product number
- HPA047607 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA047607, RRID:AB_2680101
- Product name
- Anti-DHX37
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human DHX37, Gene description: DEAH (Asp-Glu-Ala-His) box polypeptide 37, Alternative Gene Names: DDX37, KIAA1517, MGC2695, MGC4322, Validated applications: ICC, IHC, Uniprot ID: Q8IY37, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Submitted references Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome
McElreavey K, Jorgensen A, Eozenou C, Merel T, Bignon-Topalovic J, Tan D, Houzelstein D, Buonocore F, Warr N, Kay R, Peycelon M, Siffroi J, Mazen I, Achermann J, Shcherbak Y, Leger J, Sallai A, Carel J, Martinerie L, Le Ru R, Conway G, Mignot B, Van Maldergem L, Bertalan R, Globa E, Brauner R, Jauch R, Nef S, Greenfield A, Bashamboo A
Genetics in Medicine 2020;22(1):150-159
Genetics in Medicine 2020;22(1):150-159
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line MCF7 shows localization to nuclear membrane.
- Sample type
- HUMAN
Enhanced validation
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human skin and liver tissues using HPA047607 antibody. Corresponding DHX37 RNA-seq data are presented for the same tissues.
- Sample type
- HUMAN
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human skin shows nuclear membrane positivity in keratinocytes.
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human appendix shows high expression.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human liver shows low expression as expected.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human duodenum shows weak to moderate positivity in nuclear membranes in glandular cells.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human placenta shows moderate positivity in nuclear membranes in trophoblastic cells.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human skin shows moderate positivity in nuclear membranes in squamous epithelial cells.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human liver shows positivity in hepatocytes.
- Sample type
- HUMAN
