Tissue expression
Cell line expression
Protein structure
MAL
Mal, T cell differentiation proteinMVP17, VIP17
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]
Top validated antibodies |
|||||
Invitrogen Antibodies | MA5-32924 | Monoclonal |
WB
IHC
FC
|
||
Novus Biologicals | NBP2-75563 | Monoclonal |
WB
IHC
FC
|
||
Cusabio Biotech Co., Ltd | CSB-PA013372LA01HU | Polyclonal |
EL
ICC
IHC
|
||
HUABIO Research | M1701-6 | Monoclonal |
WB
IHC
FC
|
||
Biorbyt | orb45962 | Polyclonal |
EL
ICC
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider