Tissue expression
Cell line expression
Protein structure
VPS11
VPS11 core subunit of CORVET and HOPS complexesPEP5, RNF108
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Top validated antibodies |
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Proteintech Group | 19140-1-AP | 6 references | Polyclonal |
WB
EL
ICC
IP
FC
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Invitrogen Antibodies | 19140-1-AP | Polyclonal |
WB
ICC
IP
FC
OA
|
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NovoPro Bioscience Inc. | 116770 | Polyclonal |
WB
EL
ICC
IP
FC
|
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FineTest Biotech | FNab09426 | Polyclonal |
WB
EL
ICC
IP
FC
|
||
Biorbyt | orb632534 | Polyclonal |
WB
EL
ICC
IP
FC
|
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