Tissue expression
Cell line expression
Protein structure
GLRX
GlutaredoxinGRX, GRX1
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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Proteintech Group | ![]() |
3 references | Polyclonal |
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GeneTex | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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Acris Antibodies GmbH | ![]() |
Monoclonal |
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