BS6808

antibody from Bioworld Technology, Inc
Targeting: RBFOX3 FOX-3, HRNBP3, NeuN
Provider product page for BS6808
Western blot
Immunohistochemistry

Antibody data

Product number
BS6808 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NeuN polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NeuN.
Description
Fox-3, also known as NEUN, HRNBP3, RBFOX3 (RNA binding protein, fox-1) or Fox-1 homolog C, is a 350 amino acid protein that contains one RRM (RNA recognition motif) domain. Localized to both the nucleus and cytoplasm, Fox-3 is suggested to regulate alternative splicing events. Fox-3 is encoded by a gene located on human chromosome 17, which is comprised over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and LiFraumeni syndrome.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RBFOX3 protein structure - BS6808 shown in red.