Tissue expression
Cell line expression
Protein structure
TXNDC5
Thioredoxin domain containing 5EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. [provided by RefSeq, Dec 2016]
Top validated antibodies |
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Novus Biologicals | NB100-1452 | 1 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Proteintech Group | 19834-1-AP | 6 references | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | PA5-118330 | Polyclonal |
WB
ICC
IP
IHC
OA
|
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NSJ Bioreagents | RQ7712 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Everest Biotech | EB06471 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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