Tissue expression
Cell line expression
Protein structure
SPRY4
Sprouty RTK signaling antagonist 4This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]
Top validated antibodies |
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Proteintech Group | ![]() |
4 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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