PAB1714

antibody from Abnova Corporation

Targeting: HDAC6 FLJ16239, HD6, JM21, KIAA0901, PPP1R90

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB1714

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB1714, RRID:AB_1238072

Product name

HDAC6 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of HDAC6.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.

Hook SS, Orian A, Cowley SM, Eisenman RN
Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 15;99(21):13425-30

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Three proteins define a class of human histone deacetylases related to yeast Hda1p.

Grozinger CM, Hassig CA, Schreiber SL
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):4868-73

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Transcriptional control. Sinful repression.

Wolffe AP
Nature 1997 May 1;387(6628):16-7

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

The HDAC6 polyclonal antibody (Cat # PAB1714) is used in Western blot to detect HDAC6 in mouse kidney tissue lysate.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with HDAC6 polyclonal antibody (Cat # PAB1714) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)