Tissue expression
Cell line expression
Protein structure
HDAC6
Histone deacetylase 6FLJ16239, HD6, JM21, KIAA0901, PPP1R90
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | ![]() |
53 references | Polyclonal |
|
|
GeneTex | ![]() |
3 references | Monoclonal |
|
|
LSBio | ![]() |
Polyclonal |
|
||
Invitrogen Antibodies | ![]() |
Polyclonal |
|
||
Novus Biologicals | ![]() |
1 references | Monoclonal |
|