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- References [6]
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- Product number
- ABIN2844653 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Histone Deacetylase 6 (HDAC6) (AA 1182-1215), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 1182-1215, C-Term
- Antibody clone number
- RB5653
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly.
PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry.
Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.
Three proteins define a class of human histone deacetylases related to yeast Hda1p.
What's up and down with histone deacetylation and transcription?
Transcriptional control. Sinful repression.
Ran J, Yang Y, Li D, Liu M, Zhou J
Scientific reports 2015 Aug 6;5:12917
Scientific reports 2015 Aug 6;5:12917
PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry.
Wang G, Chen Q, Zhang X, Zhang B, Zhuo X, Liu J, Jiang Q, Zhang C
Journal of cell science 2013 Mar 15;126(Pt 6):1355-65
Journal of cell science 2013 Mar 15;126(Pt 6):1355-65
Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.
Hook SS, Orian A, Cowley SM, Eisenman RN
Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 15;99(21):13425-30
Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 15;99(21):13425-30
Three proteins define a class of human histone deacetylases related to yeast Hda1p.
Grozinger CM, Hassig CA, Schreiber SL
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):4868-73
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):4868-73
What's up and down with histone deacetylation and transcription?
Pazin MJ, Kadonaga JT
Cell 1997 May 2;89(3):325-8
Cell 1997 May 2;89(3):325-8
Transcriptional control. Sinful repression.
Wolffe AP
Nature 1997 May 1;387(6628):16-7
Nature 1997 May 1;387(6628):16-7
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
