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Cell line expression
Protein structure
CEBPA
CCAAT enhancer binding protein alphaC/EBP-alpha, CEBP
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]
Top validated antibodies |
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| antibodies-online |  ABIN1106663 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Acris Antibodies GmbH | AM06759SU-N |
Monoclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX60584 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Boster Biological Technology | A00386-1 |
7 references | Polyclonal |
WB
EL
ICC
FC
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| OriGene | AM06759SU-N |
Monoclonal |
WB
EL
ICC
IHC
FC
|
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