BS5510

antibody from Bioworld Technology, Inc
Targeting: CAMK2A CAMKA, CaMKIINalpha, CaMKIIα, KIAA0968
Provider product page for BS5510
Western blot
Immunohistochemistry

Antibody data

Product number
BS5510 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS5510, RRID:AB_1662796
Product name
CaMKIIÏ« (K292) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 260-310 of Human CaMKIIÏ«.
Description
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated Ï«, ÉÇ, ÎÛ and Ñ´, which may or may not be co-expressed in the same tissue type. CaMKIIÏ« is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CAMK2A protein structure - BS5510 shown in red.