Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
MCM2
Minichromosome maintenance complex component 2BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
Top validated antibodies |
|||||
| antibodies-online |  ABIN969281 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
| Proteintech Group | 10513-1-AP |
13 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
| Novus Biologicals | H00004171-M01 |
2 references | Monoclonal |
WB
EL
ICC
IP
|
|
| Invitrogen Antibodies | MA5-15895 |
3 references | Monoclonal |
WB
IHC
FC
OA
|
|
| OriGene | AM06699SU-N |
Monoclonal |
WB
EL
ICC
IHC
FC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider