Tissue expression
Cell line expression
Protein structure
EDNRB
Endothelin receptor type BETB, HSCR, HSCR2
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Top validated antibodies |
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Proteintech Group | ![]() |
6 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
4 references | Polyclonal |
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Boster Biological Technology | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Abcepta | ![]() |
Polyclonal |
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