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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- PA3-066 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Endothelin B Receptor Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Description
- PA3-066 detects Endothelin Receptor B from human, mouse, and rat samples.
- Concentration
- Conc. Not Determined
Submitted references An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1.
Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line.
Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy.
Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure.
Lee B, Shin H, Oh JE, Park J, Park M, Yang SC, Jun JH, Hong SH, Song H, Lim HJ
Autophagy 2021 Jul;17(7):1649-1666
Autophagy 2021 Jul;17(7):1649-1666
Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line.
Torres MJ, López-Moncada F, Herrera D, Indo S, Lefian A, Llanos P, Tapia J, Castellón EA, Contreras HR
Oncology reports 2021 Aug;46(2)
Oncology reports 2021 Aug;46(2)
Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy.
Lane SL, Doyle AS, Bales ES, Houck JA, Lorca RA, Moore LG, Julian CG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4283-4292
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4283-4292
Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure.
Olave N, Nicola T, Zhang W, Bulger A, James M, Oparil S, Chen YF, Ambalavanan N
American journal of physiology. Lung cellular and molecular physiology 2012 May 1;302(9):L857-65
American journal of physiology. Lung cellular and molecular physiology 2012 May 1;302(9):L857-65
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of Endothelin B Receptor in mouse brain using a polyclonal antibody (Product # PA3-066).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immnoctyochemistry of ETB in ETB-transfected cells
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Endothelin B Receptor in mouse lung using a polyclonal antibody (Product # PA3-066).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry was performed on acetone-fixed frozen mouse skin tissue sections. Tissues were fixed for 10 minutes, blocked in 3% fish gelatin for 10-20 minutes, and probed with an Isotype Control Antibody (panel A), and Endothelin Receptor A polyclonal antibody (Product # PA3-065, panel B), or an Endothelin Receptor B polyclonal antibody (Product # PA3-066, panel C) all at dilutions of 1:800 overnight at 4C. Detection was performed using a PE-conjugated anti-rabbit IgG secondary antibody at a dilution of 1:800 (red). Nuclei were stained with DAPI and tissues were visualized by fluorescence microscopy. Data courtesy of the Innovators Program.
