Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B11679 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human TRIM5 monoclonal antibody, clone 4C22I3
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4C22I3
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
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