Tissue expression
Cell line expression
Protein structure
TRIM5
Tripartite motif containing 5RNF88, TRIM5alpha
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
Top validated antibodies |
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Novus Biologicals | NBP1-76601 | 1 references | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN501058 | 4 references | Polyclonal |
WB
EL
IHC
|
|
Boster Biological Technology | A01359 | Polyclonal |
WB
EL
ICC
IHC |
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Cusabio Biotech Co., Ltd | CSB-PA874861LA01HU | 1 references | Polyclonal |
WB
EL
IHC
|
|
Abnova Corporation | MAB5551 | 2 references | Monoclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Recommended by provider