abx012281

TRIM5 antibody from Abbexa
RNF88, TRIM5alpha
Western blot
Recommended by provider
ELISA
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
abx012281
Provider
Abbexa
Product name
Tripartite Motif-Containing Protein 5 (Trim5 alpha) Antibody
Provider product page
Abbexa - abx012281
Antibody type
Monoclonal
Description
TRIM5 alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µl
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Provider Type Product Number
- No reagents -