FNab05646

antibody from FineTest Biotech

Targeting: NEDD4L KIAA0439, NEDD4-2, RSP5

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ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab05646 - Provider product page
Provider: FineTest Biotech
Product name: NEDD4L antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: neural precursor cell expressed, de velopmentally down-regulated 4-like
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

NEDD4L protein structure - FNab05646 shown in red.