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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Immunohistochemistry [4]
- Flow cytometry [2]
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- Product number
- DDX0300P-100 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal IL-3R alpha/CD123 Antibody
- Antibody type
- Monoclonal
- Description
- Ion exchange chromatography.
- Reactivity
- Human, Canine
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody.
Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol.
IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study.
Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm.
Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm.
Phenotypic localization of distinct DC subsets in mouse Peyer Patch.
Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1.
A nonredundant role for canonical NF-κB in human myeloid dendritic cell development and function.
Isolation of myeloid and plasmacytoid dendritic cells from human bronchoalveolar lavage fluid.
Dendritic cell infiltration and prognosis of early stage breast cancer.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Broughton SE, Hercus TR, Hardy MP, McClure BJ, Nero TL, Dottore M, Huynh H, Braley H, Barry EF, Kan WL, Dhagat U, Scotney P, Hartman D, Busfield SJ, Owczarek CM, Nash AD, Wilson NJ, Parker MW, Lopez AF
Cell reports 2014 Jul 24;8(2):410-9
Cell reports 2014 Jul 24;8(2):410-9
Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol.
Koehl U, Brehm C, Huenecke S, Zimmermann SY, Kloess S, Bremm M, Ullrich E, Soerensen J, Quaiser A, Erben S, Wunram C, Gardlowski T, Auth E, Tonn T, Seidl C, Meyer-Monard S, Stern M, Passweg J, Klingebiel T, Bader P, Schwabe D, Esser R
Frontiers in oncology 2013;3:118
Frontiers in oncology 2013;3:118
IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study.
Brehm C, Huenecke S, Quaiser A, Esser R, Bremm M, Kloess S, Soerensen J, Kreyenberg H, Seidl C, Becker PS, Mühl H, Klingebiel T, Bader P, Passweg JR, Schwabe D, Koehl U
PloS one 2011;6(11):e27351
PloS one 2011;6(11):e27351
Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm.
Matsuo T, Ichimura K, Tanaka T, Morizane S, Iwatsuki K, Eguchi M, Yoshino T
Journal of clinical and experimental hematopathology : JCEH 2011;51(1):49-55
Journal of clinical and experimental hematopathology : JCEH 2011;51(1):49-55
Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm.
Matsuo T, Ichimura K, Tanaka T, Morizane S, Iwatsuki K, Eguchi M, Yoshino T
Journal of clinical and experimental hematopathology : JCEH 2011;51(1):49-55
Journal of clinical and experimental hematopathology : JCEH 2011;51(1):49-55
Phenotypic localization of distinct DC subsets in mouse Peyer Patch.
Rochereau N, Verrier B, Pin JJ, Genin C, Paul S
Vaccine 2011 May 9;29(20):3655-61
Vaccine 2011 May 9;29(20):3655-61
Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1.
Bachmann M, Horn K, Rudloff I, Goren I, Holdener M, Christen U, Darsow N, Hunfeld KP, Koehl U, Kind P, Pfeilschifter J, Kraiczy P, Mühl H
PLoS pathogens 2010 Oct 14;6(10):e1001144
PLoS pathogens 2010 Oct 14;6(10):e1001144
A nonredundant role for canonical NF-κB in human myeloid dendritic cell development and function.
van de Laar L, van den Bosch A, van der Kooij SW, Janssen HL, Coffer PJ, van Kooten C, Woltman AM
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 15;185(12):7252-61
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 15;185(12):7252-61
Isolation of myeloid and plasmacytoid dendritic cells from human bronchoalveolar lavage fluid.
Tsoumakidou M, Tzanakis N, Papadaki HA, Koutala H, Siafakas NM
Immunology and cell biology 2006 Jun;84(3):267-73
Immunology and cell biology 2006 Jun;84(3):267-73
Dendritic cell infiltration and prognosis of early stage breast cancer.
Treilleux I, Blay JY, Bendriss-Vermare N, Ray-Coquard I, Bachelot T, Guastalla JP, Bremond A, Goddard S, Pin JJ, Barthelemy-Dubois C, Lebecque S
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Nov 15;10(22):7466-74
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Nov 15;10(22):7466-74
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Paraffin embedded breast cancer tissue sections
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - IHC staining of Bouin Paraffin section of human invasive breast tumor with 107D2.08 (DAB brown)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - IHC staining of frozen human tonsilsection with 106C2.02 (Fast Blue)
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Human PBMC enriched in monocytes and dendritic cells (Percollgradient) and analyzed by surface flow cytometry
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Facs staining of CD11c-sorted tonsillar cells
