10203-1-AP
antibody from Proteintech Group
Targeting: APEX1
APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1
Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10203-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10203-1-AP, RRID:AB_2057927
- Product name
- APEX1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated APEX1 antibody (Cat. #10203-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer.
LINC00470 accelerates the proliferation and metastasis of melanoma through promoting APEX1 expression.
miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway.
MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.
Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.
An integrated approach to identify critical transcription factors in the protection against hydrogen peroxide-induced oxidative stress by Danhong injection.
Suppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease.
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
miR-130a can predict response to temozolomide in patients with glioblastoma multiforme, independently of O6-methylguanine-DNA methyltransferase.
Induction of base excision repair enzymes NTH1 and APE1 in rat spleen following aniline exposure.
Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination.
Long K, Gu L, Li L, Zhang Z, Li E, Zhang Y, He L, Pan F, Guo Z, Hu Z
Cell death & disease 2021 May 18;12(6):503
Cell death & disease 2021 May 18;12(6):503
LINC00470 accelerates the proliferation and metastasis of melanoma through promoting APEX1 expression.
Huang T, Wang YJ, Huang MT, Guo Y, Yang LC, Liu XJ, Tan WY, Long JH
Cell death & disease 2021 Apr 19;12(5):410
Cell death & disease 2021 Apr 19;12(5):410
miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway.
Takagawa Y, Gen Y, Muramatsu T, Tanimoto K, Inoue J, Harada H, Inazawa J
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1494-1505
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1494-1505
MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.
Liang W, Li C, Li M, Wang D, Zhong Z
OncoTargets and therapy 2019;12:7203-7214
OncoTargets and therapy 2019;12:7203-7214
Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.
Zhang J, Geng Y, Guo F, Zhang F, Liu M, Song L, Ma Y, Li D, Zhang Y, Xu H, Yang H
Scientific reports 2017 Oct 24;7(1):13867
Scientific reports 2017 Oct 24;7(1):13867
An integrated approach to identify critical transcription factors in the protection against hydrogen peroxide-induced oxidative stress by Danhong injection.
Zhang J, Guo F, Wei J, Xian M, Tang S, Zhao Y, Liu M, Song L, Geng Y, Yang H, Ding C, Huang L
Free radical biology & medicine 2017 Nov;112:480-493
Free radical biology & medicine 2017 Nov;112:480-493
Suppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease.
Suganya R, Chakraborty A, Miriyala S, Hazra TK, Izumi T
DNA repair 2015 Mar;27:40-8
DNA repair 2015 Mar;27:40-8
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
Dong H, Shi Q, Song X, Fu J, Hu L, Xu D, Su C, Xia X, Song E, Song Y
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
miR-130a can predict response to temozolomide in patients with glioblastoma multiforme, independently of O6-methylguanine-DNA methyltransferase.
Chen H, Li X, Li W, Zheng H
Journal of translational medicine 2015 Feb 21;13:69
Journal of translational medicine 2015 Feb 21;13:69
Induction of base excision repair enzymes NTH1 and APE1 in rat spleen following aniline exposure.
Ma H, Wang J, Abdel-Rahman SZ, Boor PJ, Khan MF
Toxicology and applied pharmacology 2013 Mar 15;267(3):276-83
Toxicology and applied pharmacology 2013 Mar 15;267(3):276-83
Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination.
Masani S, Han L, Yu K
Molecular and cellular biology 2013 Apr;33(7):1468-73
Molecular and cellular biology 2013 Apr;33(7):1468-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10203-1-AP(APEX1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using APEX1 antibody 10203-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10203-1-AP(APEX1 antibody) at dilution of 1:100 (under 25x lens)
- Sample type
- tissue