DPABH-15365

antibody from Creative Diagnostics

Targeting: APEX1 APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1

No application information provided.

Antibody Data

Product number

DPABH-15365

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-15365, RRID:AB_2513379

Product name

Rabbit Anti-Human APEX1 Polyclonal antibody

Antibody type

Polyclonal

Description

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5 to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene