abx001032

antibody from Abbexa

Targeting: APEX1 APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1

Western blot

Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: abx001032 - Provider product page
Provider: Abbexa
Product name: DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody
Antibody type: Polyclonal
Description: APEX1 Antibody is a Rabbit Polyclonal antibody against APEX1. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µl
Concentration: > 1 mg/ml
Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

APEX1 protein structure - abx001032 shown in red.